MAJOR SALIVARY GLAND ULTRASOUND AND ELASTOGRAPHY FOR ASSESSMENT OF DISEASE ACTIVITY IN PATIENTS OF PRIMARY SJÖGREN’S SYNDROME
Authors: Chandwar K. et al.
Major salivary gland involvement in Sjögren’s syndrome was assessed by ultrasonography and elastography in 35 patients and compared with 55 controls. Primary Sjögren’s syndrome disease activity was assessed by ESSDAI and a patient reported index (ESSPRI). Salivary glands were assessed using Hocevar and OMERACT ultrasound scores; real time elastography was performed for the salivary glands and scored semiquantitatively.
Ultrasonographic and elastographic scores were higher in Sjögren’s cases than in controls. The Hocevar score had a very strong correlation with Sjögren’s activity, patient reported outcomes and differentiated best between high, moderate, and low disease activity. The elastography score correlated with disease activity and duration, but less than ultrasound scores.
Salivary gland ultrasound has the promise to become a feasible objective outcome parameter in Sjögren’s syndrome.