DE NOVO PSORIASIS CAN BE REPORTED AT ANY TIMEPOINT IN EARLY AXIAL SPONDYLOARTHRITIS: AN ANALYSIS OF 6 YEARS OF FOLLOW-UP OF THE DESIR COHORT
Authors: Florian LUCASSON et al.
Psoriasis (PsO) is a frequent extra-articular manifestation in axSpA with a prevalence of 9% in established axSpA. This study aimed to assess prevalence and consequences of PsO in recently diagnosed axSpA. Data from the French DESIR prospective cohort that included patients with inflammatory back pain for less than 3 years were analysed with a follow up of 6 years. Presence of PsO was assessed at baseline and at all visits. Data of 589 patients was available. The prevalence of PsO at baseline was 16.8% which increased to 26.8% at 6 years. Patients with PsO had more peripheral arthritis. However, the presence of PsO was not associated with disease activity (ASDAS-CRP), function (HAQ, BASFI), enthesitis (MASES) and spinal MRI changes (SPARCC).
This interesting study shows that PsO is frequent in early axSpA and may appear at any time during follow up. Therefore, it needs to be regularly reassessed. The presence of PsO in axSpA patients was not associated with a worse outcome, suggesting that axial involvement with or without PsO is similar. However, more studies including patients with established PsA diagnosis and axial involvement need to be done to define potential differences in spinal disease manifestations between patients with or without PsO.